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Baicalin, a flavonoid, effectively increases the levels of GSH-PX, SOD, and catalase, inhibits the infiltration of inflammatory cells such as T-lymphocytes, T-helper cells, neutrophils, and macrophages, as well as the mRNA levels of pro-inflammatory cytokines (IL-1, IL-6, MCP-1, and TNF-) [145]

PLoS One 5(7):e11838 Itoh K, Wakabayashi N, Katoh Y, Ishii T, Igarashi K, Engel JD et al (1999) Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain

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Manganese-phenolic nanoadjuvant combines sonodynamic therapy with cGAS-STING activation for enhanced cancer immunotherapy